KMID : 1100920200410030153
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Korean Journal of Family Medicine 2020 Volume.41 No. 3 p.153 ~ p.160
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Influence of Facial Flushing on Pre- or Type 2 Diabetes Risk according to Alcohol Consumption in Korean Male
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Kim Ji-Han
Kim Jong-Sung Kim Sung-Soo Jung Jin-Gyu Yoon Seok-Jun Seo Yu-Ri Lee Sa-Mi Bae Yoon-Kyung Lee Won-Jin
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Abstract
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Background: This study aims to examine the association between alcohol consumption and the risk of pre- or type 2 diabetes mellitus (T2DM) by alcohol-induced flushing response in Korean male adults, particularly based on their body mass index (BMI).
Methods: This study selected 1,030 (158 non-drinkers, 364 flushers, and 508 non-flushers) male adults who had medical checkups. A logistic regression analysis was used to compare the association between alcohol consumption and the risk of pre- or T2DM.
Results: In both the normal-weight group (BMI <23 kg/m2) and the overweight group (BMI ¡Ã23 kg/m2 and <25 kg/ m2), the flushers had a higher risk of pre- or T2DM (odds ratio, 95% confidence interval) when consuming more than 8 drinks of alcohol per week than the non-drinkers (normal-weight group: 3.43, 1.06?11.07; overweight group: 4.94, 1.56?15.67). But in the non-flushers among the normal-weight group and the overweight group, there was no significant difference compared to non-drinkers regarding the risk of pre- or T2DM. Obese flushers had a significantly higher risk of pre- or T2DM when consuming more than 4 drinks of alcohol per week than the non-drinkers (>4 and ¡Â8 drinks: 2.64, 1.10?6.36; >8 drinks: 2.42, 1.11?5.27). However, obese non-flushers had only a significant higher risk of pre- or T2DM when consuming more than 8 drinks of alcohol per week than the non-drinkers (2.72, 1.39?5.30)
Conclusion: These results suggest that obese flushers have an increased risk of developing pre- or T2DM even with less alcohol consumption.
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KEYWORD
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Alcohol Drinking, Flushing, Diabetes Mellitus, Type 2, Obesity
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